As men get older, they almost all develop enlargement of the prostate. Invariably, PSA rises as a result. PSA comes both from the prostate gland and potentially, in some cases, from prostate cancer. This what confuses things. PSA can come from both cancer and the benign prostate gland. So when checking PSA, the question should never be, “Is it above a pre-specified arbitrary threshold such as 2.5 or 4.0?” The question should be, “Is the PSA elevated above what should be expected based on the size of the prostate?” READ THE FULL ARTICLE HERE > https://www.verywell.com/the-meaning-of-psa-2782285